Welcome to MolDiag-PaCa

! Proposal for partner to join our Integrated Project !

Our consortium, active in the Sixth Framework Programme of the European Community for research, technological development and demonstration activities contributing to the creation of the European Research Area and to innovation (2002-2006), requires the participation of a new project partner to carry out certain tasks within the project.

The new partner will act as a full-member of the consortium. Its main activity will be related to WP1 goals. Because the focus of the new member will be to support WP1 goals, it is mandatory that experience in the application of epidemiological methods is demonstrated.

Full call text
Guide for proposers
Consortium Agreement
Annex II

Electronic submission is not possible for this call - only paper submission is allowed:
As the Commission`s Electronic Proposal Submission System (EPSS) is adapted to the 7th Framework Programme (FP7) you cannot use the EPSS for this FP6 call.
The Guide for Proposers states under 3.2 to complete the forms electronically, however this is not possible in this case.

For help please contact the MolDiag-Paca project office:
Dr Björg Pauling or Esther Buchholz
Tel.: ++49 (0)6421 2866853
FAX: ++49 (0)6421 2866855
Email: This email address is being protected from spambots. You need JavaScript enabled to view it. ; This email address is being protected from spambots. You need JavaScript enabled to view it.

The Clinical course on pancreatic cancer within the MolDiagPaCa network took place at the Karolinska University Hospital in Stockholm, Sweden on November 23, 2007.

The course was especially adapted to the needs of non-clinical pancreatic cancer researchers and as a refreshment course for clinicians. The contents spanned everything from clinically relevant embryology and anatomy, through diagnostics using imaging, cytology, histology and molecular tools, to current medical and surgical treatment strategies. The general theme of the course highlighted multidisciplinarity in diagnostics, decision making and treatment, and course participants took during the one day course part in the weekly multidisciplinary pancreatic cancer video conference between the hospitals in the Stockholm area.

The course covered the following program:

Clinical presentation and symptoms of pancreatic cancer.
Ake Andren-Sandberg

Anatomy and embryology of the pancreas
Ake Andren-Sandberg

Approaches to drainage of the biliary tract in pancreatic cancer
Urban Arnelo

Diagnostic imaging of pancreatic cancer
Nick Edsborg

Live Pancreatic Tumour Conference
Johan Permert and Ake Andren-Sandberg

Surgical management of pancreatic cancer
John Neoptolemos

The role of chemotherapy and radiotherapy in adjuvant, palliative . and locally advanced settings in pancreatic cancer
Pehr Lind

Summarizing case discussion
Johan Permert and Ake Andren-Sandberg

  
The Teaching course on the pathology of pancreatic tumors took place in Verona, on May 18th 2007 with 88 participants, 34 of which were not directly involved with MolDiagPaca:

In the last few years, new concepts regarding the histological and molecular subclassification of exocrine pancreatic tumors have been established. This short course, organized by experts in the field from the Pathology Departments at the Universities of Verona (Italy) and Kiel (Germany) as well as the Fundació IMIM, Barcelona (Spain), aimed at providing a review of these advances and an update with as much an emphasis in the pathological aspects as in the molecular alterations specifically associated with each tumour type. The short course wanted to address non-specialists who wish to keep abreast of pancreatic cancer molecular pathology.

The course covered the following program:

  • Where does the pancreas come from?
    Cell lineage markers of the pancreas
    Francisco X. Real, Fundació IMIM, Barcelona, Spain
      
  • Ductal adenocarcinoma
    Günther Klöppel, University Hospital Schleswig-Holstein, Kiel, Germany
      
  • Ductal type neoplasms
    Giuseppe Zamboni, University of Verona, Italy
      
  • Non-ductal type neoplasms
    Bence Sipos, University Hospital Schleswig-Holstein, Kiel, Germany
      
  • Pheno/genotype correlations
    Aldo Scarpa, University of Verona, Italy


For more details, please contact:

Prof. Aldo Scarpa
Dipartimento di Patologia
Università di Verona
Strada Le Grazie, 8
37134  Verona, Italia

Tel. +39-045-8124.043
Fax. +39-045-8027.136
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.


>> Publications


Responsible scientists

  • Stephan Hahn
    MGO, Ruhr-University, Bochum

  • Irmgard Schwarte-Waldhoff
    IMBL, Ruhr-University, Bochum

Major interests related to pancreas cancer:
  • Molecular study of ductal pancreatic adenocarcinoma
  • Molecular progression model of pancreatic carcinoma
  • Functional analysis of the tumor suppressor Smad4
  • miRNAs in pancreatic carcinoma biology
  • Analysis of secretome composition and function
  • Search for serum biomarkers
  • Co-founder of the German familial pancreatic carcinoma registry aiming at the identification of susceptibility genes for pancreatic carcinoma.

Technology:
  • Gene expression analysis of microdissected tumours, data analysis and validation using SAGE and microarray technology.
  •  Viral-shRNA technology
  • Gene transfer via transfection and retroviral transduction
  • 2D-gel analyses and quantitative 2D-Western blotting

Group members:
  • Stephan Hahn
  • Abdelouahid Maghnouj
  • Britta Redeker
  • Irmgard Schwarte-Waldhoff
  • Susanne Klein-Scory
  • Christina Eilert-Micus
  • Ongoing recruitment of personnel

Contact:
  • Irmgard Schwarte-Waldhoff (This email address is being protected from spambots. You need JavaScript enabled to view it.)
  • Stephan Hahn (This email address is being protected from spambots. You need JavaScript enabled to view it.)

Home-page:
Molecular GI-Oncology (S. Hahn): http://www.ruhr-uni-bochum.de/mgo